Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription

Deregulation of RNA polymerase III (Pol III) transcription enhances cellular tRNAs and 5S rRNA production, leading to an increase in translational capacity to promote cell proliferation, transformation and tumor formation. Phosphorylation of histone H3 (H3ph) is induced by tumor promoters (EGF, UV a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qingsong, Zhong, Qian, Evans, Austin G., Levy, Daniel, Zhong, Shuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134635/
https://www.ncbi.nlm.nih.gov/pubmed/21460852
http://dx.doi.org/10.1038/onc.2011.105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134635/
https://www.ncbi.nlm.nih.gov/pubmed/21460852
http://dx.doi.org/10.1038/onc.2011.105

Ejemplares similares