Analysis of Two Commercially Available Bortezomib Products: Differences in Assay of Active Agent and Impurity Profile

The analytical properties of two commercially available bortezomib products (VELCADE(®) and Bortenat) were compared using nuclear magnetic resonance, mass spectrometry, high-performance liquid chromatography, and gas chromatography. The data showed differences between the two products. Based on thes...

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Detalles Bibliográficos
Autores principales: Byrn, Stephen R., Tishmack, Patrick A., Milton, Mark J., van de Velde, Helgi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134677/
https://www.ncbi.nlm.nih.gov/pubmed/21455817
http://dx.doi.org/10.1208/s12249-010-9554-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134677/
https://www.ncbi.nlm.nih.gov/pubmed/21455817
http://dx.doi.org/10.1208/s12249-010-9554-1

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