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Characterization of DNA binding, transcriptional activation, and regulated nuclear association of recombinant human NFATp

BACKGROUND: NFATp is one member of a family of transcriptional activators whose nuclear accumulation and hence transcriptional activity is regulated in mammalian cells. Human NFATp exists as a phosphoprotein in the cytoplasm of naive T cells. Upon antigen stimulation, NFATp is dephosphorylated, accu...

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Detalles Bibliográficos
Autores principales: Kim, Loree J, Ferguson, Heather A, Seto, Anita G, Goodrich, James A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31347/
https://www.ncbi.nlm.nih.gov/pubmed/11231878
http://dx.doi.org/10.1186/1471-2172-1-1