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A New Validated Liquid Chromatographic Method for the Determination of Loratadine and its Impurities

An improved gradient, reversed-phase liquid chromatographic (RP-LC) method was developed and subsequently validated for the determination of Loratadine and its impurities/degradation products in pharmaceutical drug substance. Separation was achieved with Inertsil ODS-3V, 250 × 4.6 mm, 5μ column with...

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Detalles Bibliográficos
Autores principales: Ramulu, Gajjela, Ravindra Kumar, Yalavarthi, Vyas, Krishnamurthy, Suryanarayana, Mulukutla V., Mukkanti, Khagga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134850/
https://www.ncbi.nlm.nih.gov/pubmed/21773066
http://dx.doi.org/10.3797/scipharm.1012-13