Synthesis and Biological Evaluation of New 3-Phenyl-1-[(4-arylpiperazin-1-yl)alkyl]-piperidine-2,6-diones

A set of 13 alkyl derivatives of 3-phenylpiperidine-2,6-dione were synthesized. Newly obtained compounds were investigated in vitro against HIV-1 and other selected viruses. The benzyl 3f and fluorophenyl 3g derivatives showed moderate protection against CVB-2 and the compound 3g also against HSV-1....

Descripción completa

Detalles Bibliográficos
Autores principales: Bielenica, Anna, Kossakowski, Jerzy, Struga, Marta, Dybała, Izabela, Loddo, Roberta, Ibba, Cristina, La Colla, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134852/
https://www.ncbi.nlm.nih.gov/pubmed/21773062
http://dx.doi.org/10.3797/scipharm.1012-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134852/
https://www.ncbi.nlm.nih.gov/pubmed/21773062
http://dx.doi.org/10.3797/scipharm.1012-17

Ejemplares similares