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Synthesis and Biological Evaluation of New 3-Phenyl-1-[(4-arylpiperazin-1-yl)alkyl]-piperidine-2,6-diones

A set of 13 alkyl derivatives of 3-phenylpiperidine-2,6-dione were synthesized. Newly obtained compounds were investigated in vitro against HIV-1 and other selected viruses. The benzyl 3f and fluorophenyl 3g derivatives showed moderate protection against CVB-2 and the compound 3g also against HSV-1....

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Detalles Bibliográficos
Autores principales:	Bielenica, Anna, Kossakowski, Jerzy, Struga, Marta, Dybała, Izabela, Loddo, Roberta, Ibba, Cristina, La Colla, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134852/ https://www.ncbi.nlm.nih.gov/pubmed/21773062 http://dx.doi.org/10.3797/scipharm.1012-17

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