Preparation of a Nanoscaled Poly(vinyl alcohol)/Hydroxyapatite/DNA Complex Using High Hydrostatic Pressure Technology for In Vitro and In Vivo Gene Delivery

Our previous research showed that poly(vinyl alcohol) (PVA) nanoparticles incorporating DNA with hydrogen bonds obtained by high hydrostatic pressurization are able to deliver DNA without any significant cytotoxicity. To enhance transfection efficiency of PVA/DNA nanoparticles, we describe a novel m...

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Detalles Bibliográficos
Autores principales: Kimura, Tsuyoshi, Nibe, Yoichi, Funamoto, Seiichi, Okada, Masahiro, Furuzono, Tsutomu, Ono, Tsutomu, Yoshizawa, Hidekazu, Fujisato, Toshiya, Nam, Kwangwoo, Kishida, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134933/
https://www.ncbi.nlm.nih.gov/pubmed/21773048
http://dx.doi.org/10.1155/2011/962743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134933/
https://www.ncbi.nlm.nih.gov/pubmed/21773048
http://dx.doi.org/10.1155/2011/962743

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