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Preparation of a Nanoscaled Poly(vinyl alcohol)/Hydroxyapatite/DNA Complex Using High Hydrostatic Pressure Technology for In Vitro and In Vivo Gene Delivery
Our previous research showed that poly(vinyl alcohol) (PVA) nanoparticles incorporating DNA with hydrogen bonds obtained by high hydrostatic pressurization are able to deliver DNA without any significant cytotoxicity. To enhance transfection efficiency of PVA/DNA nanoparticles, we describe a novel m...
Autores principales: | Kimura, Tsuyoshi, Nibe, Yoichi, Funamoto, Seiichi, Okada, Masahiro, Furuzono, Tsutomu, Ono, Tsutomu, Yoshizawa, Hidekazu, Fujisato, Toshiya, Nam, Kwangwoo, Kishida, Akio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134933/ https://www.ncbi.nlm.nih.gov/pubmed/21773048 http://dx.doi.org/10.1155/2011/962743 |
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