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MPTP Neurotoxicity and Testosterone Induce Dendritic Remodeling of Striatal Medium Spiny Neurons in the C57Bl/6 Mouse

Nigrostriatal damage is increased in males relative to females. While estrogen is neuroprotective in females, less is known about potential protective effects of testosterone in males. We determined if castration enhances neuronal injury to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Castra...

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Detalles Bibliográficos
Autores principales: Antzoulatos, Eleni, Jakowec, Michael W., Petzinger, Giselle M., Wood, Ruth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134993/
https://www.ncbi.nlm.nih.gov/pubmed/21765998
http://dx.doi.org/10.4061/2011/138471