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Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease

The neural stem cell niches possess the regenerative capacity to generate new functional neurons in the adult brain, suggesting the possibility of endogenous neuronal replacement after injury or disease. Huntington disease (HD) is a neurodegenerative disease and characterized by neuronal loss in the...

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Detalles Bibliográficos
Autores principales: Kandasamy, Mahesh, Reilmann, Ralf, Winkler, Jürgen, Bogdahn, Ulrich, Aigner, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134994/
https://www.ncbi.nlm.nih.gov/pubmed/21766020
http://dx.doi.org/10.1155/2011/124256