The Pleiotropic Actions of Adiponectin are Initiated via Receptor-Mediated Activation of Ceramidase Activity

The adipocyte-derived secretory factor adiponectin promotes insulin sensitivity, decreases inflammation and promotes cell survival. To date, no unifying mechanism explains how adiponectin can exert such a variety of beneficial systemic effects. Here, we show that adiponectin potently stimulates a ce...

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Detalles Bibliográficos
Autores principales: Holland, William L., Miller, Russell A., Wang, Zhao V., Sun, Kai, Barth, Brian M., Bui, Hai H., Davis, Kathryn E., Bikman, Benjamin T., Halberg, Nils, Rutkowski, Joseph M., Wade, Mark R., Tenorio, Vincent M., Kuo, Ming-Shang, Brozinick, Joseph T., Zhang, Bei B., Birnbaum, Morris J., Summers, Scott A., Scherer, Philipp E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134999/
https://www.ncbi.nlm.nih.gov/pubmed/21186369
http://dx.doi.org/10.1038/nm.2277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134999/
https://www.ncbi.nlm.nih.gov/pubmed/21186369
http://dx.doi.org/10.1038/nm.2277

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