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Age-Related Changes in the Hepatic Pharmacology and Toxicology of Paracetamol

Optimal pharmacotherapy is determined when the pharmacokinetics and pharmacodynamics of the drug are understood. However, the age-related changes in pharmacokinetics and pharmacodynamics, as well as the increased interindividual variation mean optimal dose selection are a challenge for prescribing i...

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Detalles Bibliográficos
Autores principales: Mitchell, Sarah J., Kane, Alice E., Hilmer, Sarah N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135080/
https://www.ncbi.nlm.nih.gov/pubmed/21765826
http://dx.doi.org/10.1155/2011/624156