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Age-Related Changes in the Hepatic Pharmacology and Toxicology of Paracetamol
Optimal pharmacotherapy is determined when the pharmacokinetics and pharmacodynamics of the drug are understood. However, the age-related changes in pharmacokinetics and pharmacodynamics, as well as the increased interindividual variation mean optimal dose selection are a challenge for prescribing i...
Autores principales: | Mitchell, Sarah J., Kane, Alice E., Hilmer, Sarah N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135080/ https://www.ncbi.nlm.nih.gov/pubmed/21765826 http://dx.doi.org/10.1155/2011/624156 |
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