Protein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis

SHP-2 (PTPN11), a ubiquitously expressed protein tyrosine phosphatase, is critical for hematopoietic cell development and function owing to its essential role in growth factor/cytokine signaling. More importantly, germline and somatic mutations in this phosphatase are associated with Noonan syndrome...

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Detalles Bibliográficos
Autores principales: Liu, Xia, Qu, Cheng-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135119/
https://www.ncbi.nlm.nih.gov/pubmed/21799948
http://dx.doi.org/10.1155/2011/195239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135119/
https://www.ncbi.nlm.nih.gov/pubmed/21799948
http://dx.doi.org/10.1155/2011/195239

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