Regulation and Function of Syk Tyrosine Kinase in Mast Cell Signaling and Beyond

The protein tyrosine kinase Syk plays a critical role in FcεRI signaling in mast cells. Binding of Syk to phosphorylated immunoreceptor tyrosine-based activation motifs (p-ITAM) of the receptor subunits results in conformational changes and tyrosine phosphorylation at multiple sites that leads to ac...

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Detalles Bibliográficos
Autor principal: de Castro, Rodrigo Orlandini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135164/
https://www.ncbi.nlm.nih.gov/pubmed/21776385
http://dx.doi.org/10.1155/2011/507291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135164/
https://www.ncbi.nlm.nih.gov/pubmed/21776385
http://dx.doi.org/10.1155/2011/507291

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