Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death

As the ultimate electron acceptor in oxidative phosphorylation, oxygen plays a critical role in metabolism. When oxygen levels drop, heterodimeric hypoxia-inducible factor (Hif) transcription factors become active and facilitate adaptation to hypoxia. Hif regulation by oxygen requires the protein vo...

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Detalles Bibliográficos
Autores principales: Kucejova, B, Sunny, NE, Nguyen, AD, Hallac, R, Fu, X, Peña-Llopis, S, Mason, RP, DeBerardinis, RJ, Xie, X-J, DeBose-Boyd, R, Kodibagkar, VD, Burgess, SC, Brugarolas, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135264/
https://www.ncbi.nlm.nih.gov/pubmed/21217781
http://dx.doi.org/10.1038/onc.2010.587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135264/
https://www.ncbi.nlm.nih.gov/pubmed/21217781
http://dx.doi.org/10.1038/onc.2010.587

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