Cargando…
Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death
As the ultimate electron acceptor in oxidative phosphorylation, oxygen plays a critical role in metabolism. When oxygen levels drop, heterodimeric hypoxia-inducible factor (Hif) transcription factors become active and facilitate adaptation to hypoxia. Hif regulation by oxygen requires the protein vo...
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135264/ https://www.ncbi.nlm.nih.gov/pubmed/21217781 http://dx.doi.org/10.1038/onc.2010.587 |