Ionic mechanisms and Ca(2+) dynamics underlying the glucose response of pancreatic β cells: a simulation study

To clarify the mechanisms underlying the pancreatic β-cell response to varying glucose concentrations ([G]), electrophysiological findings were integrated into a mathematical cell model. The Ca(2+) dynamics of the endoplasmic reticulum (ER) were also improved. The model was validated by demonstratin...

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Detalles Bibliográficos
Autores principales: Cha, Chae Young, Nakamura, Yasuhiko, Himeno, Yukiko, Wang, JianWu, Fujimoto, Shinpei, Inagaki, Nobuya, Earm, Yung E, Noma, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135323/
https://www.ncbi.nlm.nih.gov/pubmed/21708953
http://dx.doi.org/10.1085/jgp.201110611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135323/
https://www.ncbi.nlm.nih.gov/pubmed/21708953
http://dx.doi.org/10.1085/jgp.201110611

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