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Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors

The voltage-activated sodium (Nav) channel Nav1.9 is expressed in dorsal root ganglion (DRG) neurons where it is believed to play an important role in nociception. Progress in revealing the functional properties and pharmacological sensitivities of this non-canonical Nav channel has been slow becaus...

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Detalles Bibliográficos
Autores principales: Bosmans, Frank, Puopolo, Michelino, Martin-Eauclaire, Marie-France, Bean, Bruce P., Swartz, Kenton J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135324/
https://www.ncbi.nlm.nih.gov/pubmed/21670206
http://dx.doi.org/10.1085/jgp.201110614