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Viral infection prevents diabetes by inducing regulatory T cells through NKT cell–plasmacytoid dendritic cell interplay

Type 1 diabetes (T1D) is an autoimmune disease resulting from T cell–mediated destruction of insulin-producing β cells, and viral infections can prevent the onset of disease. Invariant natural killer T cells (iNKT cells) exert a regulatory role in T1D by inhibiting autoimmune T cell responses. As iN...

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Detalles Bibliográficos
Autores principales: Diana, Julien, Brezar, Vedran, Beaudoin, Lucie, Dalod, Marc, Mellor, Andrew, Tafuri, Anna, von Herrath, Matthias, Boitard, Christian, Mallone, Roberto, Lehuen, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135349/
https://www.ncbi.nlm.nih.gov/pubmed/21444661
http://dx.doi.org/10.1084/jem.20101692