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Prostaglandin E2 suppresses the differentiation of retinoic acid–producing dendritic cells in mice and humans
The production of retinoic acid (RA) by dendritic cells (DCs) is critical for the induction of gut-tropic immune responses by driving the expression of intestinal-specific homing receptors, such as α4β7 and CCR9, upon T and B cell activation. However, how RA production is regulated during DC develop...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135350/ https://www.ncbi.nlm.nih.gov/pubmed/21444662 http://dx.doi.org/10.1084/jem.20101967 |