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Prostaglandin E2 suppresses the differentiation of retinoic acid–producing dendritic cells in mice and humans

The production of retinoic acid (RA) by dendritic cells (DCs) is critical for the induction of gut-tropic immune responses by driving the expression of intestinal-specific homing receptors, such as α4β7 and CCR9, upon T and B cell activation. However, how RA production is regulated during DC develop...

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Detalles Bibliográficos
Autores principales: Stock, Angus, Booth, Sarah, Cerundolo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135350/
https://www.ncbi.nlm.nih.gov/pubmed/21444662
http://dx.doi.org/10.1084/jem.20101967