Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

Genomic studies in human acute lymphoblastic leukemia (ALL) have revealed clonal heterogeneity at diagnosis and clonal evolution at relapse. In this study, we used genome-wide profiling to compare human T cell ALL samples at the time of diagnosis and after engraftment (xenograft) into immunodeficien...

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Detalles Bibliográficos
Autores principales: Clappier, Emmanuelle, Gerby, Bastien, Sigaux, François, Delord, Marc, Touzri, Farah, Hernandez, Lucie, Ballerini, Paola, Baruchel, André, Pflumio, Françoise, Soulier, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135355/
https://www.ncbi.nlm.nih.gov/pubmed/21464223
http://dx.doi.org/10.1084/jem.20110105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135355/
https://www.ncbi.nlm.nih.gov/pubmed/21464223
http://dx.doi.org/10.1084/jem.20110105

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