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E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells

The multifunctional E4F1 protein was originally discovered as a target of the E1A viral oncoprotein. Growing evidence indicates that E4F1 is involved in key signaling pathways commonly deregulated during cell transformation. In this study, we investigate the influence of E4F1 on tumorigenesis. Wild-...

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Detalles Bibliográficos
Autores principales: Hatchi, Elodie, Rodier, Genevieve, Lacroix, Matthieu, Caramel, Julie, Kirsh, Olivier, Jacquet, Chantal, Schrepfer, Emilie, Lagarrigue, Sylviane, Linares, Laetitia Karine, Lledo, Gwendaline, Tondeur, Sylvie, Dubus, Pierre, Sardet, Claude, Le Cam, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135361/
https://www.ncbi.nlm.nih.gov/pubmed/21708927
http://dx.doi.org/10.1084/jem.20101995