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E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells
The multifunctional E4F1 protein was originally discovered as a target of the E1A viral oncoprotein. Growing evidence indicates that E4F1 is involved in key signaling pathways commonly deregulated during cell transformation. In this study, we investigate the influence of E4F1 on tumorigenesis. Wild-...
Autores principales: | Hatchi, Elodie, Rodier, Genevieve, Lacroix, Matthieu, Caramel, Julie, Kirsh, Olivier, Jacquet, Chantal, Schrepfer, Emilie, Lagarrigue, Sylviane, Linares, Laetitia Karine, Lledo, Gwendaline, Tondeur, Sylvie, Dubus, Pierre, Sardet, Claude, Le Cam, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135361/ https://www.ncbi.nlm.nih.gov/pubmed/21708927 http://dx.doi.org/10.1084/jem.20101995 |
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