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FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa

The alveolar epithelium is composed of the flat type I cells comprising 95% of the gas-exchange surface area and cuboidal type II cells comprising the rest. Type II cells are described as facultative progenitor cells based on their ability to proliferate and trans-differentiate into type I cells. In...

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Detalles Bibliográficos
Autores principales: Liu, Yuru, Sadikot, Ruxana T., Adami, Guy R., Kalinichenko, Vladimir V., Pendyala, Srikanth, Natarajan, Viswanathan, Zhao, You-yang, Malik, Asrar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135362/
https://www.ncbi.nlm.nih.gov/pubmed/21708928
http://dx.doi.org/10.1084/jem.20102041