A biosensor generated via high throughput screening quantifies cell edge Src dynamics

Fluorescent biosensors for living cells currently require laborious optimization and a unique design for each target. They are limited by the availability of naturally occurring ligands with appropriate target specificity. Here we describe a biosensor based on an engineered fibronectin monobody scaf...

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Detalles Bibliográficos
Autores principales: Gulyani, Akash, Vitriol, Eric, Allen, Richard, Wu, Jianrong, Gremyachinskiy, Dmitriy, Lewis, Steven, Dewar, Brian, Graves, Lee M., Kay, Brian K., Kuhlman, Brian, Elston, Tim, Hahn, Klaus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135387/
https://www.ncbi.nlm.nih.gov/pubmed/21666688
http://dx.doi.org/10.1038/nchembio.585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135387/
https://www.ncbi.nlm.nih.gov/pubmed/21666688
http://dx.doi.org/10.1038/nchembio.585

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