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Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics

Dynamic microtubules facilitate chromosome arrangement before anaphase, whereas during anaphase microtubule stability assists chromosome separation. Changes in microtubule dynamics at the metaphase–anaphase transition are regulated by Cdk1. Cdk1-mediated phosphorylation of Sli15/INCENP promotes prea...

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Detalles Bibliográficos
Autores principales: Nakajima, Yuko, Cormier, Anthony, Tyers, Randall G., Pigula, Adrianne, Peng, Yutian, Drubin, David G., Barnes, Georjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135399/
https://www.ncbi.nlm.nih.gov/pubmed/21727193
http://dx.doi.org/10.1083/jcb.201009137