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Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics
Dynamic microtubules facilitate chromosome arrangement before anaphase, whereas during anaphase microtubule stability assists chromosome separation. Changes in microtubule dynamics at the metaphase–anaphase transition are regulated by Cdk1. Cdk1-mediated phosphorylation of Sli15/INCENP promotes prea...
Autores principales: | Nakajima, Yuko, Cormier, Anthony, Tyers, Randall G., Pigula, Adrianne, Peng, Yutian, Drubin, David G., Barnes, Georjana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135399/ https://www.ncbi.nlm.nih.gov/pubmed/21727193 http://dx.doi.org/10.1083/jcb.201009137 |
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