Cargando…

Caspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells

 Biochemical studies suggest that caspase activity is required for a functional mitotic checkpoint (MC) and mitotic slippage. To test this directly, we followed nontransformed human telomerase immortalized human retinal pigment epithelia (RPE-1) cells through mitosis after inhibiting or depleting se...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Kyunghee, Kenny, Alison E., Rieder, Conly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135473/
https://www.ncbi.nlm.nih.gov/pubmed/21613548
http://dx.doi.org/10.1091/mbc.E11-03-0228