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Topological arrangement of the intracellular membrane fusion machinery

Soluble N-ethylmaleimide–sensitive factor attachment protein receptors (SNAREs) form a four-helix coiled-coil bundle that juxtaposes two bilayers and drives a basal level of membrane fusion. The Sec1/Munc18 (SM) protein binds to its cognate SNARE bundle and accelerates the basal fusion reaction. The...

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Detalles Bibliográficos
Autores principales: Rathore, Shailendra S., Ghosh, Nilanjan, Ouyang, Yan, Shen, Jingshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135485/
https://www.ncbi.nlm.nih.gov/pubmed/21633111
http://dx.doi.org/10.1091/mbc.E11-03-0190