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A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells

In mammals, silencing of one of the two X chromosomes in female cells compensates for the different number of X chromosomes between the sexes. The noncoding Xist RNA initiates X chromosome inactivation. Xist spreads from its transcription site over the X chromosome territory and triggers the formati...

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Detalles Bibliográficos
Autores principales: Ng, Karen, Daigle, Nathalie, Bancaud, Aurélien, Ohhata, Tatsuya, Humphreys, Peter, Walker, Rachael, Ellenberg, Jan, Wutz, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135487/
https://www.ncbi.nlm.nih.gov/pubmed/21613549
http://dx.doi.org/10.1091/mbc.E11-02-0146