Different metastasis promotive potency of small G-proteins RalA and RalB in in vivo hamster tumor model

BACKGROUND: Previously we have shown that oncogenic Ha-Ras stimulated in vivo metastasis through RalGEF-Ral signaling. RalA and RalB are highly homologous small G proteins belonging to Ras superfamily. They can be activated by Ras-RalGEF signaling pathway and influence cellular growth and survival,...

Descripción completa

Detalles Bibliográficos
Autores principales: Rybko, Vera A, Knizhnik, Anna V, Komelkov, Andrei V, Aushev, Vasily N, Trukhanova, Lyubov S, Tchevkina, Elena M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135494/
https://www.ncbi.nlm.nih.gov/pubmed/21714887
http://dx.doi.org/10.1186/1475-2867-11-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135494/
https://www.ncbi.nlm.nih.gov/pubmed/21714887
http://dx.doi.org/10.1186/1475-2867-11-22

Ejemplares similares