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Anti-Inflammatory mechanisms of the proteinase-activated receptor 2-inhibiting peptide in human synovial cells

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease which affects the entire joint structure, including the synovial membrane. Disease progression was shown to involve inflammatory changes mediated by proteinase-activated receptor (PAR)-2. Previous studies demonstrated that PAR-2 messeng...

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Detalles Bibliográficos
Autores principales: Chen, Ta-Liang, Lin, Yung-Feng, Cheng, Chao-Wen, Chen, Shi-Yun, Sheu, Ming-Thau, Leung, Ting-Kai, Qin, Cheng-Hong, Chen, Chien-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135512/
https://www.ncbi.nlm.nih.gov/pubmed/21682866
http://dx.doi.org/10.1186/1423-0127-18-43