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A Novel Role of Protein Tyrosine Kinase2 in Mediating Chloride Secretion in Human Airway Epithelial Cells
Ca(2+) activated Cl(−) channels (CaCC) are up-regulated in cystic fibrosis (CF) airway surface epithelia. The presence and functional properties of CaCC make it a possible therapeutic target to compensate for the deficiency of Cl(−) secretion in CF epithelia. CaCC is activated by an increase in cyto...
Autores principales: | Liang, Lihua, Woodward, Owen M., Chen, Zhaohui, Cotter, Robert, Guggino, William B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135607/ https://www.ncbi.nlm.nih.gov/pubmed/21765932 http://dx.doi.org/10.1371/journal.pone.0021991 |
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