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Network Neighbors of Drug Targets Contribute to Drug Side-Effect Similarity
In pharmacology, it is essential to identify the molecular mechanisms of drug action in order to understand adverse side effects. These adverse side effects have been used to infer whether two drugs share a target protein. However, side-effect similarity of drugs could also be caused by their target...
Autores principales: | Brouwers, Lucas, Iskar, Murat, Zeller, Georg, van Noort, Vera, Bork, Peer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135612/ https://www.ncbi.nlm.nih.gov/pubmed/21765950 http://dx.doi.org/10.1371/journal.pone.0022187 |
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