Pyrone-Based Inhibitors of Metalloproteinase Types 2 and 3 May Work as Conformation-Selective Inhibitors

Matrix metalloproteinases are zinc-containing enzymes capable of degrading all components of the extracellular matrix. Owing to their role in human disease, matrix metalloproteinase have been the subject of extensive study. A bioinorganic approach was recently used to identify novel inhibitors based...

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Detalles Bibliográficos
Autores principales: Durrant, Jacob D, de Oliveira, César A F, McCammon, J Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135671/
https://www.ncbi.nlm.nih.gov/pubmed/21609408
http://dx.doi.org/10.1111/j.1747-0285.2011.01148.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135671/
https://www.ncbi.nlm.nih.gov/pubmed/21609408
http://dx.doi.org/10.1111/j.1747-0285.2011.01148.x

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