Cargando…

Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition

Neuregulin 1 (NRG1) is a secreted trophic factor that activates the postsynaptic erbB4 receptor tyrosine kinase. Both NRG1 and erbB4 have been repeatedly associated with schizophrenia, but their downstream targets are not well characterized. ErbB4 is highly abundant in interneurons, and NRG1-mediate...

Descripción completa

Detalles Bibliográficos
Autores principales: Cahill, Michael E., Jones, Kelly A., Rafalovich, Igor, Xie, Zhong, Barros, Claudia S., Müller, Ulrich, Penzes, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135693/
https://www.ncbi.nlm.nih.gov/pubmed/21483438
http://dx.doi.org/10.1038/mp.2011.35