Cargando…
Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition
Neuregulin 1 (NRG1) is a secreted trophic factor that activates the postsynaptic erbB4 receptor tyrosine kinase. Both NRG1 and erbB4 have been repeatedly associated with schizophrenia, but their downstream targets are not well characterized. ErbB4 is highly abundant in interneurons, and NRG1-mediate...
Autores principales: | Cahill, Michael E., Jones, Kelly A., Rafalovich, Igor, Xie, Zhong, Barros, Claudia S., Müller, Ulrich, Penzes, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135693/ https://www.ncbi.nlm.nih.gov/pubmed/21483438 http://dx.doi.org/10.1038/mp.2011.35 |
Ejemplares similares
-
Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory–inhibitory synapse formation in the mature cortex
por: Seshadri, Saurav, et al.
Publicado: (2015) -
Increased NRG1-ErbB4 signaling in human symptomatic epilepsy
por: Zhu, Jun-Ming, et al.
Publicado: (2017) -
NRG4-ErbB4 signaling represses proinflammatory macrophage activity
por: Schumacher, Michael A., et al.
Publicado: (2021) -
Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway
por: Sapède, Dora, et al.
Publicado: (2023) -
Expression and Localization of Neuregulin-1 (Nrg1) and ErbB2/ErbB4 Receptors in Main Endocrine Organs of the Rhesus Monkey
por: Zhao, Wei-jiang
Publicado: (2013)