Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist

The bone marrow (BM) stromal niche can protect acute lymphoblastic leukemia (ALL) cells against the cytotoxicity of chemotherapeutic agents and is a possible source of relapse. The SDF-1/CXCR4 axis is a major determinant in the crosstalk between leukemic cells and BM stroma. In the current study, we...

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Detalles Bibliográficos
Autores principales: Parameswaran, Reshmi, Yu, Min, Lim, Min, Groffen, John, Heisterkamp, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135709/
https://www.ncbi.nlm.nih.gov/pubmed/21483439
http://dx.doi.org/10.1038/leu.2011.76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135709/
https://www.ncbi.nlm.nih.gov/pubmed/21483439
http://dx.doi.org/10.1038/leu.2011.76

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