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Why Do CD8+ T Cells become Indifferent to Tumors: A Dynamic Modeling Approach
CD8+ T cells have the potential to influence the outcome of cancer pathogenesis, including complete tumor eradication or selection of malignant tumor escape variants. The Simian virus 40 large T-antigen (Tag) oncoprotein promotes tumor formation in Tag-transgenic mice and also provides multiple targ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135868/ https://www.ncbi.nlm.nih.gov/pubmed/21808621 http://dx.doi.org/10.3389/fphys.2011.00032 |