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Why Do CD8+ T Cells become Indifferent to Tumors: A Dynamic Modeling Approach

CD8+ T cells have the potential to influence the outcome of cancer pathogenesis, including complete tumor eradication or selection of malignant tumor escape variants. The Simian virus 40 large T-antigen (Tag) oncoprotein promotes tumor formation in Tag-transgenic mice and also provides multiple targ...

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Detalles Bibliográficos
Autores principales:	Campbell, Colin, Zhang, Ranran, Haley, Jeremy S., Liu, Xin, Loughran, Thomas, Schell, Todd D., Albert, Réka, Thakar, Juilee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135868/ https://www.ncbi.nlm.nih.gov/pubmed/21808621 http://dx.doi.org/10.3389/fphys.2011.00032

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