Beneficial Effects of Ethyl Pyruvate through Inhibiting High-Mobility Group Box 1 Expression and TLR4/NF-κB Pathway after Traumatic Brain Injury in the Rat

Ethyl pyruvate (EP) has demonstrated neuroprotective effects against acute brain injury through its anti-inflammatory action. The nuclear protein high-mobility group box 1 (HMGB1) can activate inflammatory pathways when released from dying cells. This study was designed to investigate the protective...

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Detalles Bibliográficos
Autores principales: Su, Xingfen, Wang, Handong, Zhao, Jinbing, Pan, Hao, Mao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136093/
https://www.ncbi.nlm.nih.gov/pubmed/21772666
http://dx.doi.org/10.1155/2011/807142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136093/
https://www.ncbi.nlm.nih.gov/pubmed/21772666
http://dx.doi.org/10.1155/2011/807142

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