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Conformational-Dependent and Independent RNA Binding to the Fragile X Mental Retardation Protein

The interaction between the fragile X mental retardation protein (FMRP) and BC1 RNA has been the subject of controversy. We probed the parameters of RNA binding to FMRP in several ways. Nondenaturing agarose gel analysis showed that BC1 RNA transcripts produced by in vitro transcription contain a po...

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Detalles Bibliográficos
Autores principales: Yan, Xin, Denman, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136132/
https://www.ncbi.nlm.nih.gov/pubmed/21772992
http://dx.doi.org/10.4061/2011/246127