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Bufalin Induces Reactive Oxygen Species Dependent Bax Translocation and Apoptosis in ASTC-a-1 Cells

Bufalin has been shown to induce cancer cell death through apoptotic pathways. However, the molecular mechanisms are not well understood. In this study, we used the confocal fluorescence microscopy (CFM) to monitor the spatio-temporal dynamics of reactive oxygen species (ROS) production, Bax translo...

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Detalles Bibliográficos
Autores principales: Sun, Lei, Chen, Tongsheng, Wang, Xiaoping, Chen, Yun, Wei, Xunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136247/
https://www.ncbi.nlm.nih.gov/pubmed/19592481
http://dx.doi.org/10.1093/ecam/nep082