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Identification of 11-amino acid peptides that disrupt Notch-mediated processes in Drosophila
BACKGROUND: The conserved Notch signaling pathway regulates cell fate decisions and maintains stem cells in multicellular organisms. Up-regulation of Notch signaling is observed in several types of cancer and is causally involved in proliferation and survival of cancer cells. Thus, it is of great in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136413/ https://www.ncbi.nlm.nih.gov/pubmed/21682860 http://dx.doi.org/10.1186/1423-0127-18-42 |