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Identification of 11-amino acid peptides that disrupt Notch-mediated processes in Drosophila

BACKGROUND: The conserved Notch signaling pathway regulates cell fate decisions and maintains stem cells in multicellular organisms. Up-regulation of Notch signaling is observed in several types of cancer and is causally involved in proliferation and survival of cancer cells. Thus, it is of great in...

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Detalles Bibliográficos
Autores principales: Pi, Haiwei, Huang, Yi-Chun, Chen, I-Chun, Lin, Chung-De, Yeh, Hsiao-Fong, Pai, Li-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136413/
https://www.ncbi.nlm.nih.gov/pubmed/21682860
http://dx.doi.org/10.1186/1423-0127-18-42