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Discovering Transcription Factor Binding Sites in Highly Repetitive Regions of Genomes with Multi-Read Analysis of ChIP-Seq Data

Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is rapidly replacing chromatin immunoprecipitation combined with genome-wide tiling array analysis (ChIP-chip) as the preferred approach for mapping transcription-factor binding sites and chromatin modifications. The sta...

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Detalles Bibliográficos
Autores principales: Chung, Dongjun, Kuan, Pei Fen, Li, Bo, Sanalkumar, Rajendran, Liang, Kun, Bresnick, Emery H., Dewey, Colin, Keleş, Sündüz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136429/
https://www.ncbi.nlm.nih.gov/pubmed/21779159
http://dx.doi.org/10.1371/journal.pcbi.1002111