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Interconversion of Functional Motions between Mesophilic and Thermophilic Adenylate Kinases
Dynamic properties are functionally important in many proteins, including the enzyme adenylate kinase (AK), for which the open/closed transition limits the rate of catalytic turnover. Here, we compare our previously published coarse-grained (double-well Gō) simulation of mesophilic AK from E. coli (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136430/ https://www.ncbi.nlm.nih.gov/pubmed/21779157 http://dx.doi.org/10.1371/journal.pcbi.1002103 |