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Proteins in the Nutrient-Sensing and DNA Damage Checkpoint Pathways Cooperate to Restrain Mitotic Progression following DNA Damage

Checkpoint pathways regulate genomic integrity in part by blocking anaphase until all chromosomes have been completely replicated, repaired, and correctly aligned on the spindle. In Saccharomyces cerevisiae, DNA damage and mono-oriented or unattached kinetochores trigger checkpoint pathways that bif...

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Detalles Bibliográficos
Autores principales: Searle, Jennifer S., Wood, Matthew D., Kaur, Mandeep, Tobin, David V., Sanchez, Yolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136438/
https://www.ncbi.nlm.nih.gov/pubmed/21779180
http://dx.doi.org/10.1371/journal.pgen.1002176