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Rotavirus Stimulates Release of Serotonin (5-HT) from Human Enterochromaffin Cells and Activates Brain Structures Involved in Nausea and Vomiting

Rotavirus (RV) is the major cause of severe gastroenteritis in young children. A virus-encoded enterotoxin, NSP4 is proposed to play a major role in causing RV diarrhoea but how RV can induce emesis, a hallmark of the illness, remains unresolved. In this study we have addressed the hypothesis that R...

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Detalles Bibliográficos
Autores principales: Hagbom, Marie, Istrate, Claudia, Engblom, David, Karlsson, Thommie, Rodriguez-Diaz, Jesus, Buesa, Javier, Taylor, John A., Loitto, Vesa-Matti, Magnusson, Karl-Eric, Ahlman, Håkan, Lundgren, Ove, Svensson, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136449/
https://www.ncbi.nlm.nih.gov/pubmed/21779163
http://dx.doi.org/10.1371/journal.ppat.1002115