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Early In Vitro Differentiation of Mouse Definitive Endoderm Is Not Correlated with Progressive Maturation of Nuclear DNA Methylation Patterns

The genome organization in pluripotent cells undergoing the first steps of differentiation is highly relevant to the reprogramming process in differentiation. Considering this fact, chromatin texture patterns that identify cells at the very early stage of lineage commitment could serve as valuable t...

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Detalles Bibliográficos
Autores principales: Tajbakhsh, Jian, Gertych, Arkadiusz, Fagg, W. Samuel, Hatada, Seigo, Fair, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136488/
https://www.ncbi.nlm.nih.gov/pubmed/21779341
http://dx.doi.org/10.1371/journal.pone.0021861